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Silence Therapeutics PLC - ADR
72 Hammersmith Road
Phone: +44 2034576900p:+44 2034576900 London, W14 8TH  United Kingdom Ticker: SLNSLN
Business Summary
Silence Therapeutics plc is a United Kingdom-based biotechnology company. The Company is developing medicines by harnessing the body's natural mechanism of RNA interference, or RNAi, to inhibit the expression of specific target genes. The Company's mRNAi GOLD (GalNAc Oligonucleotide Discovery) platform can be used to create siRNAs (short interfering RNAs) that precisely target and silence disease-associated genes in the liver. Its wholly owned product candidates include zerlasiran (SLN360), which is designed to address the high and prevalent unmet medical need in reducing cardiovascular risk in people born with high levels of lipoprotein (a), and SLN124, which is designed to address hematological diseases. It also maintains ongoing research and development collaborations with AstraZeneca, Mallinckrodt Pharmaceuticals and Hansoh Pharma, among others. These collaborations collectively represent up to 16 pipeline programs. Its other pipeline products include SLN-HAN-1 and SLN-HAN-2.

Scores and Ratings
FRISK®
Score		 Z''
Score		 PAYCE®
Score		 DBT
Index		 Moody's
Rating		 Fitch
Rating		 DBRS
Rating
YesYes-----

Financials, News and Filings
Latest
Statement		 Last
Audit
News		 SEC
Filings		 Bankruptcy
Filings		 Suit &
Judgment
Filings		 Tax
Lien
Filings
6/30/202412/31/2023Yes----

Industries
SIC Code Description
2834 Pharmaceutical preparations
8731 Commercial physical and biological research

Officers and Directors

Title
Name
Age		 Title
Date		 Start
Date
Non-Executive Chairman of the Board Iain G.Ross 9/14/2020 4/25/2019
President, Chief Executive Officer, Executive Director Craig A.Tooman 59 2/21/2022 1/6/2021
Chief Technical Operations Officer J.PGabriel 11/1/2022 11/1/2022
7 additional Officers and Directors records available in full report.

General Information
Number of Employees: 115 (As of 12/31/2023)
Outstanding Shares: 140,393,470 (As of 6/30/2024)
Stock Exchange: NASD
Fax Number: +44 7957318494


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Wednesday, November 20, 2024